and while you're at disassembling anyway, why don't you launch the system without the case, just with a normal A500 PSU
"I've completed a full tear-down and reassembly"
Umm...it's all back together again...and funny...did the 'odd' mouse thing described above on first boot 
I'm away house shopping today, but "I'll be back"
How about this?
I have the first A500 board, the one where I first saw the issue...
I can stuff it back in it's ugly old plastic coffin, with a second Indivision ECS V2 and a second ACE2b.
Alas...I don't have a second ACA500+ ... so I'll move this ACA500+ and this Micromys over and whip out my decrepit Amiga power brick.
Having already seen this behaviour with the Micromys on that board, using the described setup, I'm reasonably confident "the walk" won't be for nothing, as the odd behaviour is sure to show up...
For a couple of months, this system ran on my desk like this; while I waited for the CM1500 case to show up...

Powered by the stock power supply...
And I never said a word about the mouse, because, who's gonna show a picture of a system running like that and say "Help me Obi-Wan"
I'd point out that the ACA500+, ACE2b and Indivision ECS V2 have been 'otherwise happy' to live in the case and consume the power that I've provided them...old A500 plastic box, logic board screwed into an A500 bottom shield, new CM1500 case, old Commodore PSU, new PSU made by me, they all worked the same. Having looked at the support history of all the iComp designed contraptions involved here, the Micromys does not seem like it should be anywhere near the 'weakest link'. There are so many other iComp contraptions in this setup that are sensitive to power, shielding, grounding, that they would likely be going haywire, if there was such a problem.
"Fault Isolation" is indeed a good diagnostic practice, but it can also lead to reduction to the absurd if you let it.
I'm going to get a couple other PS/2 mice and start there, because I think that really would be the simplest thing first.
If it turns out it's the mouse, my best guess is it's protocol related, I'll send it to you, so you can see what it does differently, and maybe increase Micromys compatibility with what's available on the market...which isn't a whole lot these days.
If the problem continues with other mice, then I'll proceed with the second A500 in a plastic box as outlined above.
Chat you in a couple days 