Here's an initial port of the Sega Megadrive / Gensis core to V2 hardware. This is merely a port of the V1 core, and doesn't incorporate any of the recent upstream improvements.
retroramblings.net/snapshots/fpgagen_chameleonv2_20190505.zip
Please test and let me know if you encounter any problems. It should support CDTV pads, C64 joystick (though only one button) and PS/2 keyboard mapping for both players.