I noticed that quite a few of my G64 images do not work in the TC64's emulated drive. By this I mean they appear completely corrupted, you cannot get a directory listing or load any file. It's as if the image contained random data and you get nothing but read-error returned by the DOS.
In looking at the ones that worked and ones that didn't, it seemed that the ones that did not were images where the GCR data wasn't aligned on an 8-bit boundary like you would see if it were read and framed by the shift-register of the 1541 and thus in images created by Zoomfloppy. These images were created by flux copiers such as Kryoflux and SuperCard-Pro and converted to G64. They work fine in Vice emulator as it does bitwise rotation of the image, but I'm guessing TC64 does not? I don't have any other explanation. This kind of alignment is required to properly represent protections such as the offset sync mark on many earlier V-Max games such as Bop'N Rumble, Defender of the Crown, and Into the Eagle's Nest.
My config is:
NTSC C64C
TC64v2 in cartridge mode
Single emulated drive device #8